|   From the Trenches

Scaling Culture With Growth: How to maintain your startup’s “special sauce”

I’ve been thinking a lot about growth, and for good reason: Dyne is in the midst of a significant scale-up.

By Joshua Brumm, CEO of Dyne Therapeutics, as part of the From The Trenches feature of LifeSciVC

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  |   From the Trenches

Ode to Scientists

In the fall of 2019, I wrote a blog called Ode to Patients.  As stresses from many directions have mounted over the past 12 months, it seems that paying heed to another group now makes sense: scientists.

By Samantha Truex, CEO of Quench Bio, as part of the From The Trenches feature of LifeSciVC

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  |   From the Trenches

Strategy Sync vs. Time Sink with Your Board

If we could quantify the time and money impact of the resources invested in quarterly Board meeting preparation, I wonder if we would “invest” so much in the process?

If we knew the dollar impact and opportunity cost of CEOs’ overpreparation for Board members’ potential questions, would we shift focus to efforts that would result in more tangible value for the business?

By Rene Russo, CEO of Xilio Therapeutics, as part of the From The Trenches feature of LifeSciVC. 

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  |   From the Trenches

Selective Allosteric TYK2 Inhibitors

Family Oddball, and a New Class of Safe Oral Autoimmune & Inflammatory Disease Treatment with Blockbuster Potential

On day one of the JPM 2021 conference, CEO Giovanni Caforio of Bristol Myers Squibb – inheritor of Celgene’s former first presenting slot – took the virtual stage to highlight BMS’s biggest new products.

By Jeb Keiper, CEO of Nimbus Therapeutics, as part of the From The Trenches feature of LifeSciVC.

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  |   LifeSciVC

Personal Reflection: Empathy In The Workplace

By Bruce Booth, DPhil, Partner

Just before I chaired a Board meeting last year, I spent a frustratingly painful hour going through many of the uncomfortable details of my divorce process and a set of emotional custody issues with my lawyers. Immediately after hanging up, with only minutes of transition, I put on my best poker face and dropped into the Board zoom with one of my portfolio companies. With a smile and some attempt at humor, I kicked off the meeting. I chaired it fine, I think, but throughout the meeting my head was rattling around with angst, disappointment, frustration, and all the other negative energy that many divorces are bathed in. I’m sure it affected my engagement in this instance, and in many others with similar dynamics for the past couple years. And my blogging has suffered. Life isn’t always easy, and divorces are emotional rollercoasters.

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